Evaluating the Analgesic Effects of Opioids in Birds
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چکیده
The analgesic effect of opioids varies widely among vertebrate species. This may be due to the distribution, number and type of opioid receptors within the brain. In general, distribution of opioid receptor types is conserved across species in brainstem and spinal cord areas but varies significantly in the forebrain [2]. In the pigeon forebrain 76% of the total opioid receptors are kappa [2]. Early discrimination trials concluded that pigeons may not be able to discriminate mu and kappa agonists and the opioid receptors may share a common mechanism of action [4].
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تاریخ انتشار 2002